Introduction
- Bacteriocidal
- Non B lactam
- Brand ambassador of Gram (+)ve bacteria.
Covers:
Gram +ve cocci, Gram -ve bacilli Including:
- MRSA
- MRSE
- Listeria
- Enterococcus
+ এগুলোর পাশাপাশি একটা anaerobe – Clostridium
Dosen’t Cover:
- Atypical bacteria
- Gram -ve bacteria
Always given IV, except for Pseudomembranous colitis by Clostridium, where it is given orally.
Indication:
- Stahphylococcal infection including MRSA, MRSE.
- Some form of Endocarditis
- Prosthetic valve impaltation
- Pseudomembranous colitis (Oral)
Dose:
TDS due to its short half life.
Teicoplanin is a similar drug, with long half life, which can be given once daily. However, Teicoplanin is not approved in USA.
Renal excretion, so dose adjustment is necessary in renal impairment.
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